Welcome to this Contemporary Pediatrics poll. Take a look at the following case below. After reading through the description, choose a multiple choice answer and try to guess the correct patient diagnosis.

Then, come back to ContemporaryPediatrics.com on Friday, April 4, 2025 at 12:00 PM ET or later for the full case presentation, differential diagnoses, and the correct patient diagnosis. The full case will be presented as a separate article on our home page.

This case was presented by Rylee Moody, BS; Mary Gibney, MD;and Elaine Siegfried, MD.

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Figure 1A - Present case

Image credit: Author provided

The case:

A 21-month-old girl presented with a history of "skin tags" involving her gluteal cleft,noted at birth (Figure 1A). She was otherwise healthy and developing normally. Notably, her older sister had a confirmed history of molluscum contagiosum (MC).

Skin exam featured three prominent2-4 mm soft, pedunculated papules within the superior aspect of hergluteal cleft, as well as sparsely scattered 1-2 mmpapulescharacteristic of MC on the gluteal prominences and in mirror distribution on the perianal mucosa.

Visit ContemporaryPediatrics.com on Friday, April 4, 2025 at 12:00 PM ET or later for the full case presentation, differential diagnoses, and the correct patient diagnosis.

The full case will be presented as a separate article on our home page.

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Want more puzzler case studies? Click here.