RX Review: Emerging research shaping the future of food allergy care in 2025
In the final part of this 5-part series, panelists discuss new allergy treatments such as Xolair, early immunotherapy, and their broader impact.
Emerging research in food allergy and anaphylaxis is set to reshape clinical practice. In this Contemporary Pediatrics and HCPLive RX Review discussion, moderator Brian Schroer, MD, discusses key advancements with Colleen Kraft, MD, and Russell Traister, MD.
Traister highlights new treatment approaches, including patch therapies and the combined use of Xolair (omalizumab) with oral immunotherapy. He notes ongoing research to determine the best sequencing for these treatments and their long-term efficacy.
Kraft emphasizes the potential for these therapies to address asthma, atopic dermatitis, and food allergies. She envisions a future where comprehensive allergy management improves overall quality of life for children and families.
Schroer points to the growing implementation of early immunotherapy in children under 4 years.1 Studies suggest that early treatment may significantly reduce peanut allergies, allowing many children to live without dietary restrictions. He also acknowledges the financial challenges associated with Xolair, noting that its widespread use could pose cost concerns for the healthcare system.
Kraft adds that while oral immunotherapy is more affordable, its time-intensive nature limits accessibility in primary care. She stresses that improved allergy prevention and treatment will ultimately benefit families by easing childcare and school challenges. The panel concludes by emphasizing the need for continued innovation and education in allergy management.
Our Panelists:
Brian Schroer, MD, is an allergist-immunologist at the Cleveland Clinic Children's Hospital. Board-certified in internal medicine, pediatrics, and allergy and immunology, Schroer serves as the moderator for this panel discussion.
Colleen Kraft, MD, is a clinical professor of Pediatrics at the Keck School of Medicine of USC and an attending physician at the Children’s Hospital Los Angeles. In addition to these roles, Kraft is also the former president of the American Academy of Pediatrics.
Russell Traister, MD, is a pediatric allergy and immunology specialist at Allegheny Health Network’s Pediatric Institute. Board certified in allergy, immunology, and internal medicine, Traister serves as the third panelist for our discussion.
Reference:
Loke P, Vickery BP, Jones SM, Peters RL, Roberts G, Koplin JJ. Food Allergen Immunotherapy in Preschool Children: Do We Have the Evidence?. J Allergy Clin Immunol Pract. 2023;11(4):1028-1035. doi:10.1016/j.jaip.2023.01.005
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