Neonatal/Perinatology

A large population-based study found that first-trimester tetracycline exposure does not elevate the risk of major congenital malformations, though specific risks for nervous system and eye anomalies warrant further research.

A study of over 1 million births in Quebec reveals that pregnant women with hidradenitis suppurativa face increased risks of pregnancy complications and long-term health issues for both themselves and their offspring.

In a recent global review, significant annual increases in the mean term birthweight were reported, indicating worldwide public health impacts.

Findings from a newly-published study revealed that newborn metabolic profiles may identify infants at an increased risk for SIDS shortly after birth.

Investigators concluded that findings suggest the need for improved public health messaging regarding fish intake guidelines for pregnant persons.

The investigational drug demonstrated promise in mitigating hemolytic disease of the fetus and newborn by blocking harmful antibodies.

Findings show that that feeding mode is by far the most defining factor for microbial composition," wrote the study authors.

Dressing changes are less painful for neonates and minimize the risk of bleeding or oozing. In addition, complete wound coverage with the dressing helps prevent dehydration and heat loss.

A cohort analysis shows state Medicaid programs could assure young children with sickle cell disease receive cost-efficient and critical care in a timely fashion.

Approximately 40% of patients who receive PN in the United States as an intravenous source of nourishment are under 18 years of age.

Research in AJOG: Maternal hyperoxygenation doesn't boost neonatal Apgar scores in pathologic fetal heart rate tracing, showing no FiO2 benefit.

A recent study revealed that employing maternal heart rate monitoring alongside fetal heart rate monitoring during labor significantly decreases the incidence of neonatal encephalopathy and severe neonatal acidemia.

The FTD will allow the development and review timeline of nipocalimab to accelerate. It is granted to drugs with the potential to treat severe conditions and provide unmet vital medical needs.

Walgreens and CVS pharmacies are set to dispense mifepristone in select states, aiming to address legal complexities and enhance accessibility amidst ongoing regulatory and legal battles.

New neonatal incubators from Drager and certain GE Healthcare incubators do not need to be run for a week prior to clinical use, according to a healthcare provider update from the FDA.

In a poster abstract presented at the American Society of Health-System Pharmacists Midyear Clinical Meeting & Exhibition held in Anaheim, California, stress ulcer prophylaxis (SUP) did not appear to provide benefit for prevention of gastrointestinal bleeding and did not increase SUP-associated adverse effects.

A recent study in JAMA Network Open investigates the impact of extrauterine placental perfusion versus delayed cord clamping on hematocrit levels in newborns, shedding light on potential alternatives for optimizing infant outcomes during birth.

A recent study was highlighted at the 2023 American Academy of Pediatrics National Conference & Exhibition that shed light on the long-term impact of very preterm birth on the health-related quality of life (HRQOL) of infants and identified key determinants.

Vana Papevangelou, MD, PhD, presented current and upcoming strategies to prevent congenital cytomegalovirus (CMV) infections in neonates at IDWeek 2023.

Francheska M. Merced-Nieves, PhD, Assistant professor, Departments of Pediatrics and the Institute for Exposomic Research of Environmental Medicine & Public Health, Icahn School of Medicine at Mount Sinai, explains the associations prenatal exposure to a metal mixture and the potential negative effects for the infant.

In a recent study, improved neurodevelopmental outcomes were seen in children aged 2 years whose mothers received a Mediterranean diet or mindfulness-based stress reduction intervention during pregnancy.

In the 18 studies that assessed the efficacy of closing a patent ductus arteriosus after 1 course of acetaminophen treatments, the results demonstrated that both oral and IV preparations were more effective than placebo.

In a recent study, no significant differences in math and reading test scores were found among children born at term with different gestational ages.

The FDA has identified NOxBOX Ltd’s recall of NOxBOXi Nitric Oxide Delivery System as a Class I recall. Affected devices to the newborn and neonate patient populations can cause nitric oxide therapy interruptions because of a check valve misalignment. As of July 13, 2023, no injuries or deaths have been reported according to the federal agency.

In a recent study, monozygotic twins with an increased birth rate had fewer autism traits and intellectual disability ratings.

In a recent study, increased risks of adverse pregnancy, delivery, and neonatal outcomes were found among women with obsessive-compulsive disorder.

In a recent study, maternal fever was more common in patients who received epidural analgesia and was associated with adverse neonatal outcomes.

In a recent study, centers performing open spina bifida repair saw variations in policies for fetal resuscitation.

In a recent study, states enacting a 20-week abortion ban from 2011 to 2018 had increased rates of neonatal Down Syndrome diagnoses.

Multiple studies have indicated a greater risk of neonatal morbidity and mortality when births occur in out-of-hospital settings.