Polycystic Ovary Syndrome: Update on the Pros and Cons of Treatment Options
March 1st 2007ABSTRACT: Polycystic ovary syndrome (PCOS) is the most common endocrinopathy among females of reproductive age. In adolescents, PCOS often manifests with irregular menses, hirsutism, and acne. Despite general agreement that the metabolic derangements of PCOS arise during puberty, the condition is diagnosed more often in adults than in adolescents. Treatment is focused on weight loss, menstrual cycle regulation, and amelioration of physical symptoms. Acute symptoms can be managed with combination oral contraceptives and antiandrogens and potentially with insulin-sensitizing drugs. Lifestyle modification, especially in overweight patients, can reduce symptoms and help prevent long-term health consequences.
Case in Point: Sandifer Syndrome
March 1st 2007A previously healthy full-term, 30-week- old infant presents to the emergency department after a 30-minute episode in which he turned blue after a feeding. His mother states that the infant was also stiff, that he "arched his back," and that his eyes "had a blank look." There was no twitching associated with this episode, and the infant had no fever, cold symptoms, or any sick contact.