FDA to review four TNF drugs for cancer risk
The Food and Drug Administration has begun a safety review of four tumor necrosis factor (TNF) inhibitors, after receiving over reports of cancer caused in children who were taking them.
The Food and Drug Administration has begun a safety review of four tumor necrosis factor (TNF) inhibitors, after receiving over reports of cancer caused in children who were taking them.
The four drugs are certolizumab (Cimzia), etanercept (Enbrel), adalimumab (Humira), and infliximab (Remicade). They treat a variety of immune system disorders, including Crohn's disease, plaque psoriasis, and juvenile idiopathic, rheumatoid, and psoriatic arthritis.
Lymphomas were half of the reported cancers: others included leukemia and melanoma.
All four drugs already carry warnings that they have been linked to cancers. There have been over 30 reports of children's cancers over the last decade. FDA is also requiring certolizumab manufacturer UCB Pharma to conduct a long-term risk study, which will take 10 years to complete.
Having "the talk" with teen patients
June 17th 2022A visit with a pediatric clinician is an ideal time to ensure that a teenager knows the correct information, has the opportunity to make certain contraceptive choices, and instill the knowledge that the pediatric office is a safe place to come for help.
Meet the Board: Vivian P. Hernandez-Trujillo, MD, FAAP, FAAAAI, FACAAI
May 20th 2022Contemporary Pediatrics sat down with one of our newest editorial advisory board members: Vivian P. Hernandez-Trujillo, MD, FAAP, FAAAAI, FACAAI to discuss what led to her career in medicine and what she thinks the future holds for pediatrics.
