Vol 35 No. 04

A meta-analysis of 12 studies of the risk of death after a brief resolved unexplained event (BRUE) found that such an event does not increase an infant’s risk of dying during his or her first year. The American Academy of Pediatrics (AAP) introduced BRUE, a sudden alteration in an infant’s breathing, color, tone, or responsiveness, as a replacement for “apparent life-threatening event” (ALTE) in a 2016 clinical practice guideline.

An 11-month-old boy was brought to the doctor by anxious parents for the evaluation of persistent diaper dermatitis. Despite trying multiple barrier creams and over-the-counter antifungal products, the rash did not resolve.