Stress ulcer prophylaxis does not provide prevention of gastrointestinal bleeding in neonates
December 4th 2023In a poster abstract presented at the American Society of Health-System Pharmacists Midyear Clinical Meeting & Exhibition held in Anaheim, California, stress ulcer prophylaxis (SUP) did not appear to provide benefit for prevention of gastrointestinal bleeding and did not increase SUP-associated adverse effects.
AAP cautions against low-carbohydrate diets for children at risk for diabetes
December 1st 2023According to the American Academy of Pediatrics (AAP), it is recommended that 45% to 65% of total daily calories come from carbohydrates, though very low-carbohydrate diets allow for 20 to 50 grams per day.
Yamo enrolls final patient of phase 2 study of L1-79 to treat symptoms of ASD
November 29th 2023Yamo Pharmaceuticals has initiated a phase 3 readiness program for L1-79, following the enrollment of its final patient in a phase 2 study evaluating the autism spectrum disorder (ASD) treatment for patients aged 2 to 21 years.
Pz-cel granted FDA Priority Review to treat recessive dystrophic epidermolysis bullosa
November 28th 2023The FDA granted Priority Review to pz-cel following a phase 1/2 and a pivotal phase 3 study in which the treatment for recessive dystrophic epidermolysis bullosa (RDEB) demonstrated wound healing and pain reduction.
Worsening severity of AD in children associated with increased comorbidity onset risk
November 27th 2023Of patients in the atopic dermatitis (AD) cohort, 36.6% developed at least 1 comorbidity amid follow-up compared to 28.5% in the non-AD reference cohort, investigators of a Sweden, nationwide, population-based cohort study found.
Improved sickle cell disease in children associated with hydroxyurea treatment
November 27th 2023A recent study underscores the significant disease burden in children with sickle cell disease, urging consideration for earlier and higher-dose hydroxyurea treatment to alleviate morbidity, especially in those with HbSS/Sβ0 thalassemia.
Treatment-to-target strategies decreased pain for children with non-systemic JIA
November 8th 2023The study authors sought to compare pain scores over 2 years in 3 treatment strategies in non-systemic JIA patients who were treated to target aimed at inactive disease, and to determine the effect of inactive disease and time to inactive disease on pain.
High BMI associated with increased risk of type 1 diabetes
November 8th 2023In a systematic and meta-analysis review of cohort studies that featured nearly 1.7 million individuals, study authors concluded that there is an association between high body mass index (BMI) and an increased risk of incident type 1 diabetes (T1D).
Are you administering the correct dose of Moderna’s COVID-19 vaccine?
November 6th 2023The FDA was made aware some health care providers had administered the full single dose vial of the vaccine, which contains “notably more” volume than the 0.25 mL volume indicated for children aged 6 months to 11 years.