New topline phase 3 data for tapinarof cream 1% to treat AD in children
January 11th 2024New interim data from the on-going, long-term extension ADORING 3 study and from an integrated analysis of the entire ADORING development program revealed efficacy and safety using tapinarof cream 1% continued beyond 8 weeks of treatment.
Safety and efficacy of FDA-approved linaclotide reinforced with new phase 3 data
January 10th 2024Compared to placebo, linaclotide demonstrated a statistically significant and clinically meaningful improvement in spontaneous bowel movement(s) (SBM) frequency rate, and was subsequently approved by the FDA in June 2023.
FDA accepts sBLA for NexoBrid to remove eschar in pediatric thermal burn patients
January 10th 2024MediWound Ltd is seeking to expand the label for NexoBrid, already approved for eschar removal in adult patients, to the pediatric indication after the FDA accepted a supplemental Biologics Application for this patient population.
Maternal folic acid linked to reduced Kawasaki disease risk in infants
January 9th 2024A study revealed that higher maternal folic acid levels and frequent supplementation during pregnancy can significantly lower the risk of Kawasaki disease in infants, highlighting the potential protective role of folic acid.
Increased household transmission of influenza A observed in 2021-2022 vs prior seasons
January 9th 2024Though more research is needed to determine reasons for the association, a study published in JAMA Network revealed the 2021-2022 influenza season was associated with a significantly higher household transmission risk compared to pre-pandemic seasons.
Seizures could be the cause of many sudden unexplained deaths in toddlers
January 9th 2024The study authors noted that without video evidence, seizures would not have been implicated in death investigations and that seizure-related deaths are underrecognized in patients with epilepsy and in those without.
Marstacimab reduces annualized bleeding in hemophilia A and B patients
January 8th 2024Marstacimab reduced the annualized bleeding rate (ABR) by 35% and nearly 92%, respectively, compared to routine prophylaxis and on-demand treatment in hemophilia A and B patients without inhibitors, according to Pfizer.
Diagnostic procedure: lung biopsy may be reliable for neonatal patients in critical situations
January 8th 2024“However, in older children, the decision to perform a lung biopsy should be carefully considered, weighting the potential benefits against the associated risks," stated the investigative team.
FDA approves prescription berdazimer gel, 10.3% to treat molluscum contagiosum
January 5th 2024Berdazimer gel, 10.3% demonstrated positive, topline data in the phase 3 randomized clinical B-SIMPLE4 trial (NCT04535531) that featured a total of 891 patients aged 6 months or older who had 3 to 709 raised molluscum contagiosum lesions.
Higher burden of care associated with loneliness in caregivers of children with type 1 diabetes
January 4th 2024Results demonstrated that caregiver burden scored a 2.14 on the caregiver burden scale, which is within the average burden level, though a higher burden of care is associated with a higher sense of loneliness. These results can help health care professionals develop a family-centered treatment plan.
Inequities in breastfeeding rates among racial and ethnic communities in the United States
January 4th 2024A recent study by the CDC indicates differing rates of breastfeeding initiation among various racial and ethnic groups, underscoring the significance of meticulous data disaggregation for precise insights into public health.
Specialty infant formula voluntarily recalled due to possible bacterial contamination
January 2nd 2024More than 675,000 cans of specialty infant formula for cow’s milk allergy have been voluntarily recalled by Reckitt/Mead Johnson Nutrition because of a possible contamination with Cronobacter sakazakii.