Gastroenterology

The approval makes dupilumab the first and only treatment specifically indicated for eosinophilic esophagitis (EoE) patients aged 1 to 11 years that weigh at least 33 lbs (15 kg).

Though the association of BMI gain and 100% fruit juice in children was “small,” authors concluded their findings support public health guidance to limit consumption of the beverage to prevent overweight and obesity.

Compared to placebo, linaclotide demonstrated a statistically significant and clinically meaningful improvement in spontaneous bowel movement(s) (SBM) frequency rate, and was subsequently approved by the FDA in June 2023.

The United States Preventive Services Task Force (USPSTF) is planning to recommend that comprehensive, intensive behavioral interventions be the primary effective intervention for weight loss in children and adolescents with high body mass indexes (BMI).

Data from a 4-year trial of preschool-aged children offers new insight into the effects of initiating obesity management strategies among children in early life.

Investigators concluded that clinicians should be aware, for individuals with a prior rotavirus-associated hospitalization, of an elevated susceptibility to autoimmune disease in these patients. 

To combat this association, study investigators concluded a reduction in daily soft drink consumption should be a priority among school-going adolescents.

This recent research indicates the necessity for clinicians to be aware of the higher autoimmune disease susceptibility of those with previous rotavirus-associated hospitalization.

A new scientific statement indicates lifestyle interventions may change the trajectory of obesity-related cardiovascular risk from onset in childhood to manifestation in adulthood.

GLP-1 receptor agonists, used to treat diabetes, are now also being used for obesity in children and adolescents.

An analysis of data from nearly 750,000 adolescents from more than 40 countries offers insight into the changing, and possibly inaccurate, perceptions of healthy body weight among younger people since the turn of the century.

Links between teenager anxiety and gastrointestinal (GI) issues are the subject of this Contemporary Pediatrics® interview with Julia Anderson, MD, MSCI; and Sara Francis, PhD.

Based on results from a recent C.S. Mott Children’s Hospital National Poll on Children’s Health, find out how comfortable parents feel when it comes to abdominal pain in their child, and how likely they are to handle the issue themselves, or to reach out to a health care provider for help.

The American Medical Association is asking doctors to scale back the use of the body mass index (BMI) when assessing obesity and health in patients, noting it should be used jointly with other measurements, and not solely. 

This decision marks the first functional constipation treatment approved by the FDA for this patient population.

Providers who refer patients for clinical hypnosis must ensure that the chosen hypnotherapist has appropriate knowledge about the patient’s gastrointestinal condition and has conducted clinical hypnosis for it.

A new analysis found differences in the gut bacteria seen in adults with obesity, suggesting that changes in the gut microbiota that predispose to adult obesity may begin in early childhood.

Erica Gunderson, PhD, MS, MPH, RD, senior research scientist, Kaiser Permanente Northern California Division of Research, professor of Health Systems Science, Kaiser Permanente Bernard J. Tyson School of Medicine discusses how cardiometabolic health and childhood obesity are linked to breastfeeding. Gunderson also discusses receiving the 2022-2023 March of Dimes Agnes Higgins Award at the Pediatric Academic Societies meeting in Washington, DC on April 30, 2023.

In addition, 17 female patients who completed PENFS showed improvements in various symptoms, such as pain, disability, and catastrophizing, while carbohydrate degradation and LCFA synthesis pathways decreased in the post-treatment and follow-up analysis.

In a recent study, children of women in an IR-hyperglycemic group were 5 times more likely to develop childhood obesity than those from a control group.

Children exposed to maternal COVID-19 during pregnancy showed lower birth weight, lower birth BMI, and accelerated postnatal weight gain, compared with those unexposed.

Built environments, but not social and economic environments, were negatively associated with BMI and overweight or obesity status, with a stronger association among adolescents with longer exposure to their built environment.

In a recent study, reductions in body mass index along with further beneficial effects were found when using oral butyrate supplementation for treating pediatric obesity.

In part 1 of our obesity series, Katherine H. Saunders, MD, DABOM, discusses methods of treating pediatric obesity, including medicines approved by the FDA and the advantages of Intellihealth.

A study from Slovenia suggests a physical activity intervention that would require physical activity every day while at school was effective for reducing BMI and reversing obesity in young children.

Youth who underwent metabolic and bariatric surgery as teenagers are at heightened risk for alcohol use, according to a recent study.

A sugary drinks tax in England may have prevented over 5,000 cases of obesity a year in older girls, but had no significant association with obesity levels in year six boys or younger children.

A follow-up to a Texas Sprouts gardening intervention found improved glucose control and reduced low-density lipoprotein cholesterol in individuals at a high risk of metabolic diseases.

The February 2023 edition of Pediatrics included evidence-based guidelines from the American Academy of Pediatrics on evaluating and treating obesity in children and adolescents.

Using data from more than 25,000 preschool-aged children in Sweden provides an overview in trends of weight gain and BMI changes that may have impacted pediatric populations during the COVID-19 pandemic.