April 18th 2025
The sBLA for dupilumab (Dupixent) was supported by data from the phase 3 LIBERTY-CUPID clinical program in patients with uncontrolled CSU.
A Tethered Approach to Type 2 Diabetes Care – Connecting Insulin Regimens with Digital Technology
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Surv.AI Says™: What Clinicians and Patients Are Saying About Glucose Management in the Technology Age
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Addressing Healthcare Inequities: Tailoring Cancer Screening Plans to Address Inequities in Care
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Cases and Conversations™: Applying Best Practices to Prevent Shingles in Your Practice
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A guide to caring for cancer survivors
August 1st 2005Children and adolescents who have had a malignancy are at risk of medical, psychological, and social late effects of their disease and its treatment. If you're aware of potential problems and how to screen for them, you can help ensure the good health and proper development of these vulnerable youngsters.
Photo Essay: Hyperpigmented Macules
August 1st 2005This 13-year-old boy has a Becker nevus--also called Becker melanosis, because the lesions do not contain nevus cells. This common lesion is characterized by the abrupt onset of hyperpigmentation that gradually expands; it appears at or before adolescence.
Photoclinic: Klippel-Trenaunay-Weber Syndrome
August 1st 2005The parents of this 2-year-old boy brought their son for evaluation of swelling of the right leg and excoriation and serosanguineous discharge from the ankle region of 3 days' duration.The child had had a hemangioma of the right ankle since birth. Subsequently, there was gradual spread of the lesion along the leg to the buttocks.
Photoclinic: Second-Degree Sunburn
August 1st 2005After spending a day at the beach, a 12-year-old boy presented with a second-degree sunburn and blisters on his shoulders (A). According to his mother, he had used sunscreen. The child was not taking any medications. Except for a significant number of moles, his skin was normal.
Photoclinic: Common Wart (Verruca Vulgaris)
August 1st 2005This 14-year-old girl had first noticed the well-circumscribed, roughened, irregular growth on her right middle finger 6 months earlier. The lesion had progressively enlarged. The girl's mother had a similar, but smaller, lesion on the left elbow. Alexander K. C. Leung, MD, and Justine H. S. Fong, MD, of Calgary, Alberta, diagnosed verruca vulgaris. This proliferative, hyperkeratotic, exophytic lesion is most commonly caused by human papillomavirus types 2 and 4.
Osteogenesis Imperfecta in a 3-Year-Old Boy
August 1st 2005A 3-year-old boy who presents with blue sclerae and a history of tibial fracture following a minor trau- ma (jump from a height of less than 18 inches). Has a long-standing complaint of back pain. Mother remarks that the boy bruises easily. Medical history otherwise unremarkable.
(Don't) get your peanuts! Research effort convened to tackle food allergy
July 5th 2005There's but limited advice you can dispense to parents of your patients who have a potentially life-threatening food allergy: Avoid, avoid, avoid! Yet there's cause for optimism today among stymied clinicians and the four percent of Americans who have a food allergy—often to nuts or shellfish: a new Food Allergy Research Consortium convened at the end of June by the federal government, and led by a prominent pediatrician and food allergy expert, has been charged with, first, conducting basic, clinical, and epidemiologic studies aimed at developing therapies to treat and prevent food allergy and, second, developing educational programs aimed at parents, children, and healthcare providers.
Fighting a rising tide of MRSA infection in the young
July 1st 2005The incidence of community-based methicillin-resistant Staphylococcus aureus (MRSA) infection in healthy children is increasing. This review discusses possible reasons for that rise, reviews antibiotic susceptibility patterns, and presents management guidelines.
Pediatrics Update: Methicillin-Resistant Staphylococcus aureus: How Best to Treat Now?
June 1st 2005Over the past 5 years, methicillin-resistant Staphylococcus aureus (MRSA) isolates have become widespread throughout the United States as well as the world.1 In some regions, including our own Gulf Coast, MRSA accounts for the majority of S aureus isolates recovered from patients with community-acquired infections.
Photoclinic: Acanthosis Nigricans in an Adolescent With Metabolic Syndrome
June 1st 2005During a routine annual checkup, a 5-ft 8-in, 94.5-kg (210-lb) 13-year-old girl was noted to have a hyperpigmented "dirty" lesion on the back of her neck. The girl's parents were also obese. Her mother had type 2 diabetes mellitus.
Aplasia Cutis Congenita in an Infant
June 1st 2005Developmentally healthy 9-month-old boy brought for evaluation of congenital pale pink 2-cm plaque on left parietal scalp. Lesion relatively unchanged since birth. No history of birth trauma or scalp electrode monitoring in the intrapartum period. Mother denied varicella infection during pregnancy.
Jaundice in a newborn: How to head off an urgent situation. Second of two parts.
May 1st 2005Extreme hyperbilirubinemia must be treated swiftly to prevent neurologic damage. Here are methods for determining a newborn's likelihood of developing severe jaundice and guidelines for treating those judged at greatest risk.